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Registro Completo |
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Biblioteca(s): |
Embrapa Pecuária Sudeste. |
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Data corrente: |
08/03/2021 |
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Data da última atualização: |
26/04/2021 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
LIMA, C. S.; PEREIRA, M. H.; ALEMÁN GAINZA, Y.; HOSTE, H.; REGASINI, L. O.; CHAGAS, A. C. de S. |
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Afiliação: |
CAROLINE SPRENGEL LIMA, UNESP; MATHEUS HENRIQUE PEREIRA, UNESP; YOUSMEL ALEMÁN GAINZA, CNPq; HERVÉ HOSTE, INRA; LUÍS OCTAVIO REGASINI, UNESP; ANA CAROLINA DE SOUZA CHAGAS, CPPSE. |
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Título: |
Anthelmintic effect of Pterogyne nitens (Fabaceae) on eggs and larvae of Haemonchus contortus: analyses of structure-activity relationships based on phenolic compounds. |
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Ano de publicação: |
2021 |
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Fonte/Imprenta: |
Industrial Crops and Products, v.164, june 2021, 113348. |
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Páginas: |
8 p. |
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Idioma: |
Inglês |
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Conteúdo: |
Due to high prevalence and large pathogenicity, Haemonchus contortus is the main gastrointestinal nematode in tropical and subtropical regions. This species is responsible for severe economic losses to sheep and goat breeders in Brazil. The control of this parasite is currently compromised, mainly, due to anthelmintic resistance. In the search for natural anthelmintic alternatives, Pterogyne nitens, a native Brazilian tree with potential ethnopharmacological activity, has been identified. The aim of this study was to evaluate the anthelmintic activity of ethanolic extracts and phenolic compounds from P. nitens, as well as two commercial flavonoids (chrysin and morin), to derive the chemical structure and anthelmintic activity. The ovicidal and larvicidal activity of ethanolic extracts from leaves (EEL) and fruits (EEFR), as well as natural compounds from P. nitens on H. contortus were evaluated through egg hatch assay (EHA) and larval development assay (LDA). The results showed that all extracts, especially the phenolic compounds were active in the EHA and LDA. The egg hatch inhibitory effects of EEL (EC50 = 316 μg/mL) were more potent than EEFR (EC50 = 512 μg/mL). However, larval development inhibitory effects of EEL (EC50 = 47 μg/mL) and EEFR (EC50 = 35 μg/mL) were similar. Among the compounds, the flavones (sorbifolin, pedalitin, and chrysin) did not have inhibitory effects on egg hatching but presented some activity against larval development of H. contortus. In contrast, the flavonols (quercetin, rutin, and morin) showed high activity in the EHA but were inactive in the LDA. The addition of at hydroxyl group and rutinose group to the flavonoid structure increased the ovicidal and larvicidal activity, respectively. The phenolic acids showed potent anthelmintic activity: caffeic acid, ferulic acid, and gallic acid had the highest anthelmintic effects, presenting EC50 values of 1.48, 0.56, and 4.93 μg/mL in the EHA; and 31, 22, and 33 μg/mL in the LDA, respectively. These results suggest that P. nitens might be a source of effective alternative compounds to control H. contortus. MenosDue to high prevalence and large pathogenicity, Haemonchus contortus is the main gastrointestinal nematode in tropical and subtropical regions. This species is responsible for severe economic losses to sheep and goat breeders in Brazil. The control of this parasite is currently compromised, mainly, due to anthelmintic resistance. In the search for natural anthelmintic alternatives, Pterogyne nitens, a native Brazilian tree with potential ethnopharmacological activity, has been identified. The aim of this study was to evaluate the anthelmintic activity of ethanolic extracts and phenolic compounds from P. nitens, as well as two commercial flavonoids (chrysin and morin), to derive the chemical structure and anthelmintic activity. The ovicidal and larvicidal activity of ethanolic extracts from leaves (EEL) and fruits (EEFR), as well as natural compounds from P. nitens on H. contortus were evaluated through egg hatch assay (EHA) and larval development assay (LDA). The results showed that all extracts, especially the phenolic compounds were active in the EHA and LDA. The egg hatch inhibitory effects of EEL (EC50 = 316 μg/mL) were more potent than EEFR (EC50 = 512 μg/mL). However, larval development inhibitory effects of EEL (EC50 = 47 μg/mL) and EEFR (EC50 = 35 μg/mL) were similar. Among the compounds, the flavones (sorbifolin, pedalitin, and chrysin) did not have inhibitory effects on egg hatching but presented some activity against larval development of H. co... Mostrar Tudo |
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Palavras-Chave: |
Egg hatch assay (EHA); Ethanolic extracts; In vitro; Larval development assay (LDA). |
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Thesaurus Nal: |
Anthelmintics; Phenolic compounds. |
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Categoria do assunto: |
H Saúde e Patologia |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/221715/1/AnthelminticEffectPterogyne.pdf
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Marc: |
LEADER 03007naa a2200265 a 4500
001 2130547
005 2021-04-26
008 2021 bl uuuu u00u1 u #d
100 1 $aLIMA, C. S.
245 $aAnthelmintic effect of Pterogyne nitens (Fabaceae) on eggs and larvae of Haemonchus contortus$banalyses of structure-activity relationships based on phenolic compounds.$h[electronic resource]
260 $c2021
300 $a8 p.
520 $aDue to high prevalence and large pathogenicity, Haemonchus contortus is the main gastrointestinal nematode in tropical and subtropical regions. This species is responsible for severe economic losses to sheep and goat breeders in Brazil. The control of this parasite is currently compromised, mainly, due to anthelmintic resistance. In the search for natural anthelmintic alternatives, Pterogyne nitens, a native Brazilian tree with potential ethnopharmacological activity, has been identified. The aim of this study was to evaluate the anthelmintic activity of ethanolic extracts and phenolic compounds from P. nitens, as well as two commercial flavonoids (chrysin and morin), to derive the chemical structure and anthelmintic activity. The ovicidal and larvicidal activity of ethanolic extracts from leaves (EEL) and fruits (EEFR), as well as natural compounds from P. nitens on H. contortus were evaluated through egg hatch assay (EHA) and larval development assay (LDA). The results showed that all extracts, especially the phenolic compounds were active in the EHA and LDA. The egg hatch inhibitory effects of EEL (EC50 = 316 μg/mL) were more potent than EEFR (EC50 = 512 μg/mL). However, larval development inhibitory effects of EEL (EC50 = 47 μg/mL) and EEFR (EC50 = 35 μg/mL) were similar. Among the compounds, the flavones (sorbifolin, pedalitin, and chrysin) did not have inhibitory effects on egg hatching but presented some activity against larval development of H. contortus. In contrast, the flavonols (quercetin, rutin, and morin) showed high activity in the EHA but were inactive in the LDA. The addition of at hydroxyl group and rutinose group to the flavonoid structure increased the ovicidal and larvicidal activity, respectively. The phenolic acids showed potent anthelmintic activity: caffeic acid, ferulic acid, and gallic acid had the highest anthelmintic effects, presenting EC50 values of 1.48, 0.56, and 4.93 μg/mL in the EHA; and 31, 22, and 33 μg/mL in the LDA, respectively. These results suggest that P. nitens might be a source of effective alternative compounds to control H. contortus.
650 $aAnthelmintics
650 $aPhenolic compounds
653 $aEgg hatch assay (EHA)
653 $aEthanolic extracts
653 $aIn vitro
653 $aLarval development assay (LDA)
700 1 $aPEREIRA, M. H.
700 1 $aALEMÁN GAINZA, Y.
700 1 $aHOSTE, H.
700 1 $aREGASINI, L. O.
700 1 $aCHAGAS, A. C. de S.
773 $tIndustrial Crops and Products$gv.164, june 2021, 113348.
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Registro original: |
Embrapa Pecuária Sudeste (CPPSE) |
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Registro Completo
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
06/01/2015 |
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Data da última atualização: |
17/05/2022 |
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Tipo da produção científica: |
Artigo em Anais de Congresso |
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Autoria: |
SOUZA, V. de; BENEVIDES, S. D.; OLIVEIRA, L. S.; OLIVEIRA, E. L. de; CADENA, J. E. B.; OLIVEIRA, C. J. B. de; ARAÚJO, M. E. de; COSTA, V. M. D. |
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Afiliação: |
VIVIANE DE SOUZA, CNPC; SELENE DAIHA BENEVIDES, CNPC; LEANDRO SILVA OLIVEIRA, CNPC; EDUARDO LUIZ DE OLIVEIRA, CNPC; José Everaldo Barbosa Cadena, EMATER-PB; Celso José Bruno de Oliveira, Universidade Federal da Paraíba (UFPB) - Areia, PB.; Maria Evelane de Araújo, Graduação - Instituto Superior de Teologia Aplicada (INTA) - Sobral, CE.; Viviane Maria Dias Costa, Graduação - INTA - Sobral, CE. |
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Título: |
Sistema de Produção Integrada do leite de cabra na região do Cariri Paraibano. |
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Ano de publicação: |
2014 |
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Fonte/Imprenta: |
In: CONGRESSO NORDESTINO DE PRODUÇÃO ANIMAL, 9., 2014, Ilhéus. Produção animal: novas diretrizes; trabalhos apresentados. Ilhéus: SNPA, 2014. 3 f. |
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Idioma: |
Português |
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Conteúdo: |
Resumo: O Sistema Agropecuário de Produção Integrada (SAPI) é uma política pública voltada à obtenção de alimentos seguros, para atender exigências sanitárias, tecnológicas, ambientais e sociais deste novo mercado consumidor. O sistema emprega tecnologias, as quais permitem a aplicação de Boas Práticas Agropecuárias (BPA) e controle efetivo de todo o processo produtivo. Idealizou-se o presente estudo, com o objetivo de implementar medidas de BPA em duas propriedades do Cariri Paraibano, as quais se tornarão Unidades Técnicas de Referência Local (UTRL) para o Sistema Agropecuário de Produção Integrada de Caprinocultura Leiteira. Os resultados obtidos demonstraram que esse modelo de produção tem potencial para proporcionar uma nova competitividade para a produção de leite de cabra e derivados. [Integrated production system for goat milk in the cariri region of paraíba, Brazil]. Abstract: Goat milk is an inclusion product in family agriculture within the institutional and other new types of markets. In northeastern Brazil where as a rule all goat milk goes to school meal-provisions, goat breeding in family homesteads is being developed in expansion hubs even though such features as quantity and quality required improvement. The Agricultural-Stockbreeding System of Integrated Production (SAPI) is a government policy for safe food deemed to comply with sanitary, technological, environmental and social requirements of the new consumer market. The system employs technologies through the application of Good Agricultural Practices (GAP) and efficient control throughout the production process. Current analysis aims at deploying GAP on two farms in the Cariri region of the state of Paraíba, Brazil, which will become the Technical Units for Local Reference for the Agricultural-Stockbreeding System of Integrated Production. Results show that the production model is capable of providing new competitiveness for the production of goat milk and derived products . MenosResumo: O Sistema Agropecuário de Produção Integrada (SAPI) é uma política pública voltada à obtenção de alimentos seguros, para atender exigências sanitárias, tecnológicas, ambientais e sociais deste novo mercado consumidor. O sistema emprega tecnologias, as quais permitem a aplicação de Boas Práticas Agropecuárias (BPA) e controle efetivo de todo o processo produtivo. Idealizou-se o presente estudo, com o objetivo de implementar medidas de BPA em duas propriedades do Cariri Paraibano, as quais se tornarão Unidades Técnicas de Referência Local (UTRL) para o Sistema Agropecuário de Produção Integrada de Caprinocultura Leiteira. Os resultados obtidos demonstraram que esse modelo de produção tem potencial para proporcionar uma nova competitividade para a produção de leite de cabra e derivados. [Integrated production system for goat milk in the cariri region of paraíba, Brazil]. Abstract: Goat milk is an inclusion product in family agriculture within the institutional and other new types of markets. In northeastern Brazil where as a rule all goat milk goes to school meal-provisions, goat breeding in family homesteads is being developed in expansion hubs even though such features as quantity and quality required improvement. The Agricultural-Stockbreeding System of Integrated Production (SAPI) is a government policy for safe food deemed to comply with sanitary, technological, environmental and social requirements of the new consumer market. The system employs technologies throug... Mostrar Tudo |
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Palavras-Chave: |
Boas Práticas Agropecuárias; CAEV; SAPI. |
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Thesagro: |
Caprino; Leite de cabra; Linfadenite Caseosa; Produção Integrada; Produção leiteira. |
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Thesaurus NAL: |
Caseous lymphadenitis; Goat milk; Milk production. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/114892/1/aac-Sistema.pdf
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Marc: |
LEADER 03057nam a2200325 a 4500
001 2004424
005 2022-05-17
008 2014 bl uuuu u00u1 u #d
100 1 $aSOUZA, V. de
245 $aSistema de Produção Integrada do leite de cabra na região do Cariri Paraibano.$h[electronic resource]
260 $aIn: CONGRESSO NORDESTINO DE PRODUÇÃO ANIMAL, 9., 2014, Ilhéus. Produção animal: novas diretrizes; trabalhos apresentados. Ilhéus: SNPA, 2014. 3 f.$c2014
520 $aResumo: O Sistema Agropecuário de Produção Integrada (SAPI) é uma política pública voltada à obtenção de alimentos seguros, para atender exigências sanitárias, tecnológicas, ambientais e sociais deste novo mercado consumidor. O sistema emprega tecnologias, as quais permitem a aplicação de Boas Práticas Agropecuárias (BPA) e controle efetivo de todo o processo produtivo. Idealizou-se o presente estudo, com o objetivo de implementar medidas de BPA em duas propriedades do Cariri Paraibano, as quais se tornarão Unidades Técnicas de Referência Local (UTRL) para o Sistema Agropecuário de Produção Integrada de Caprinocultura Leiteira. Os resultados obtidos demonstraram que esse modelo de produção tem potencial para proporcionar uma nova competitividade para a produção de leite de cabra e derivados. [Integrated production system for goat milk in the cariri region of paraíba, Brazil]. Abstract: Goat milk is an inclusion product in family agriculture within the institutional and other new types of markets. In northeastern Brazil where as a rule all goat milk goes to school meal-provisions, goat breeding in family homesteads is being developed in expansion hubs even though such features as quantity and quality required improvement. The Agricultural-Stockbreeding System of Integrated Production (SAPI) is a government policy for safe food deemed to comply with sanitary, technological, environmental and social requirements of the new consumer market. The system employs technologies through the application of Good Agricultural Practices (GAP) and efficient control throughout the production process. Current analysis aims at deploying GAP on two farms in the Cariri region of the state of Paraíba, Brazil, which will become the Technical Units for Local Reference for the Agricultural-Stockbreeding System of Integrated Production. Results show that the production model is capable of providing new competitiveness for the production of goat milk and derived products .
650 $aCaseous lymphadenitis
650 $aGoat milk
650 $aMilk production
650 $aCaprino
650 $aLeite de cabra
650 $aLinfadenite Caseosa
650 $aProdução Integrada
650 $aProdução leiteira
653 $aBoas Práticas Agropecuárias
653 $aCAEV
653 $aSAPI
700 1 $aBENEVIDES, S. D.
700 1 $aOLIVEIRA, L. S.
700 1 $aOLIVEIRA, E. L. de
700 1 $aCADENA, J. E. B.
700 1 $aOLIVEIRA, C. J. B. de
700 1 $aARAÚJO, M. E. de
700 1 $aCOSTA, V. M. D.
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Embrapa Caprinos e Ovinos (CNPC) |
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